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Tinghong Ye Selected Research

Focal Adhesion Protein-Tyrosine Kinases

1/2022Design, synthesis and biological evaluation of 7-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)-2,3-dihydro-1H-inden-1-one derivatives as potent FAK inhibitors for the treatment of ovarian cancer.

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Tinghong Ye Research Topics

Disease

38Neoplasms (Cancer)
10/2023 - 08/2013
15Neoplasm Metastasis (Metastasis)
06/2022 - 01/2014
10Pulmonary Fibrosis (Fibrosing Alveolitis)
04/2024 - 01/2017
10Breast Neoplasms (Breast Cancer)
11/2023 - 01/2014
9Fibrosis (Cirrhosis)
04/2024 - 01/2018
8Melanoma (Melanoma, Malignant)
06/2022 - 02/2016
7Autoimmune Hepatitis
12/2023 - 01/2018
7Liver Cirrhosis (Hepatic Cirrhosis)
01/2023 - 08/2017
7Inflammation (Inflammations)
12/2022 - 02/2015
4Colorectal Neoplasms (Colorectal Cancer)
11/2019 - 01/2014
3Idiopathic Pulmonary Fibrosis
01/2023 - 11/2021
3Autoimmune Diseases (Autoimmune Disease)
01/2021 - 04/2020
3Liver Diseases (Liver Disease)
10/2020 - 04/2018
2Triple Negative Breast Neoplasms
12/2021 - 07/2021
2Hypoxia (Hypoxemia)
01/2021 - 04/2014
2Hepatitis
01/2021 - 10/2019
2Carcinoma (Carcinomatosis)
07/2018 - 10/2016
2Pancreatic Neoplasms (Pancreatic Cancer)
07/2016 - 12/2014
2Lung Neoplasms (Lung Cancer)
04/2014 - 08/2013
1Interstitial Lung Diseases (Interstitial Lung Disease)
04/2024
1Genomic Instability
11/2023
1Silicosis
12/2022
1Lung Injury
12/2022
1Stomach Neoplasms (Stomach Cancer)
10/2022
1Diabetic Nephropathies (Diabetic Nephropathy)
02/2022
1Ovarian Neoplasms (Ovarian Cancer)
01/2022
1Lung Diseases (Lung Disease)
01/2022
1Pathologic Processes
11/2021
1Systemic Lupus Erythematosus (Libman-Sacks Disease)
10/2020

Drug/Important Bio-Agent (IBA)

11Bleomycin (Blenoxane)FDA LinkGeneric
04/2024 - 01/2017
9Proteins (Proteins, Gene)FDA Link
01/2022 - 02/2017
7Concanavalin AIBA
12/2023 - 01/2018
5NiclosamideFDA Link
04/2024 - 01/2014
5nifuroxazide (Akabar)IBA
01/2023 - 02/2016
4MicroRNAs (MicroRNA)IBA
01/2021 - 01/2018
3Transforming Growth Factors (Transforming Growth Factor)IBA
04/2024 - 04/2014
3CollagenIBA
04/2024 - 01/2022
3Carbon Tetrachloride (Tetrachloromethane)IBA
11/2022 - 01/2018
3Matrix Metalloproteinases (MMPs)IBA
11/2021 - 02/2016
3pectolinarigeninIBA
10/2020 - 01/2019
3Reactive Oxygen Species (Oxygen Radicals)IBA
10/2020 - 01/2015
3cryptotanshinoneIBA
10/2020 - 08/2016
3Caspase 3 (Caspase-3)IBA
09/2019 - 09/2017
2Phosphotransferases (Kinase)IBA
10/2022 - 10/2018
2Therapeutic UsesIBA
02/2022 - 09/2017
2VimentinIBA
01/2022 - 02/2016
2snake venom protein C activatorIBA
11/2021 - 10/2020
2indium-bleomycinIBA
07/2021 - 01/2017
2Trifluoperazine (Stelazine)FDA LinkGeneric
01/2021 - 01/2019
2Antipsychotic Agents (Antipsychotics)IBA
01/2021 - 01/2019
2Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA
10/2020 - 04/2014
2hinokiflavoneIBA
09/2019 - 07/2018
2LigandsIBA
01/2019 - 08/2013
2Liposomes (Liposome)IBA
09/2017 - 01/2017
2Sirolimus (Rapamycin)FDA Link
12/2016 - 04/2014
2ZLD1039IBA
02/2016 - 01/2016
1Lipid NanoparticlesIBA
04/2024
1Proteasome Endopeptidase Complex (Proteasome)IBA
11/2023
1Proteasome InhibitorsIBA
11/2023
1DNA (Deoxyribonucleic Acid)IBA
11/2023
1Biomarkers (Surrogate Marker)IBA
10/2023
1benzothiopheneIBA
01/2023
1AcidsIBA
01/2023
1ferulic acid (sodium ferulate)IBA
01/2023
1nintedanibIBA
01/2023
1pirfenidoneIBA
01/2023
1AntioxidantsIBA
12/2022
1Nicotinamide MononucleotideIBA
12/2022
1Silicon Dioxide (Silica)FDA LinkGeneric
12/2022
1Food IngredientsIBA
12/2022
1Glutathione (Reduced Glutathione)IBA
12/2022
1FlavonoidsIBA
12/2022
1Ascorbic Acid (Vitamin C)FDA LinkGeneric
12/2022
1PolyphenolsIBA
12/2022
1tranilastIBA
11/2022
1tyrosine receptor (receptor, tyrosine)IBA
10/2022
1AminesIBA
10/2022
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
10/2022
1Hydroxyproline (4 Hydroxyproline)IBA
02/2022
1Focal Adhesion Protein-Tyrosine KinasesIBA
01/2022
1Platelet-Derived Growth FactorIBA
01/2022
1Cadherins (E-Cadherin)IBA
01/2022
1Casein Kinase II (Casein Kinase 2)IBA
12/2021
1Matrix Metalloproteinase InhibitorsIBA
11/2021
1N-methyladenosineIBA
11/2021
1Histones (Histone)IBA
11/2021
1MTOR InhibitorsIBA
07/2021
1Cytostatic AgentsIBA
07/2021
1IndazolesIBA
04/2021
1Circular RNAIBA
01/2021
1Endothelial Protein C ReceptorIBA
01/2021
1Neuropilin-1IBA
01/2021
1Glucose (Dextrose)FDA LinkGeneric
01/2021
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
10/2020
1galanginIBA
10/2020

Therapy/Procedure

24Therapeutics
04/2024 - 01/2014
4Oral Administration
01/2023 - 08/2014
3Immunotherapy
10/2023 - 10/2020
3Drug Therapy (Chemotherapy)
01/2021 - 09/2017
1Intraperitoneal Injections
02/2022